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ARFGAP2 Antibody

  • 货号：
    CSB-PA137594
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using CSB-PA137594(ARFGAP2 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: A431 and hela cell, Primary antibody: CSB-PA137594(ARFGAP2 Antibody) at dilution 1/200 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 15 seconds
  • 其他：

产品详情

  • Uniprot No.：
    Q8N6H7
  • 基因名：
  • 别名：
    ADP-ribosylation factor GTPase-activating protein 2 antibody; ARF GAP 2 antibody; ARFG2_HUMAN antibody; ARFGAP2 antibody; FLJ14576 antibody; FLJ26000 antibody; GTPase activating protein ZNF289 antibody; GTPase-activating protein ZNF289 antibody; IRZ antibody; Nbla10535 antibody; Zfp289 antibody; Zinc finger protein 289 antibody; Zinc finger protein 289 ID1 regulated antibody; ZNF289 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthetic peptide of Human ARFGAP2
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:20-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Implicated in coatomer-mediated protein transport between the Golgi complex and the endoplasmic reticulum. Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes.
  • 基因功能参考文献：
    1. analysis of the distinct role of subcomplexes of the COPI coat in the regulation of ArfGAP2 activity PMID: 22375848
    2. ARFGAP2 and ARFGAP3 are essential for COPI coat assembly on the Golgi membrane of living cells. PMID: 20858901
    3. human ARFGAP2 and ARFGAP3 are associated with COP-I-coated vesicles and function in COP I traffic PMID: 17760859
  • 亚细胞定位：
    Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Also found on peripheral punctate structures likely to be endoplasmic reticulum-Golgi intermediate compartment.
  • 数据库链接：

    HGNC: 13504

    OMIM: 606908

    KEGG: hsa:84364

    STRING: 9606.ENSP00000434442

    UniGene: Hs.436204