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ARHGEF16 Antibody

  • 货号：
    CSB-PA008867
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    Q5VV41
  • 基因名：
    ARHGEF16
  • 别名：
    ARHGEF 16 antibody; ARHGEF16 antibody; ARHGG_HUMAN antibody; Ephexin 4 antibody; Ephexin-4 antibody; EPHEXIN4 antibody; GEF16 antibody; NBR antibody; Putative Neuroblastoma Protein antibody; Rho guanine exchange factor (GEF) 16 antibody; Rho guanine nucleotide exchange factor (GEF) 16 antibody; Rho guanine nucleotide exchange factor 16 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human ARHGEF16.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Guanyl-nucleotide exchange factor of the RHOG GTPase stimulating the exchange of RHOG-associated GDP for GTP. May play a role in chemotactic cell migration by mediating the activation of RAC1 by EPHA2. May also activate CDC42 and mediate activation of CDC42 by the viral protein HPV16 E6.
  • 基因功能参考文献：
    1. Sixty-four novel structural analogues of Y27632 were synthesized and tested for their ability to persistently inhibit the transformation of NIH3T3 cells by Rho guanidine exchange factor 16 (ARHGEF16) or Ras. PMID: 19707205
    2. These data suggest that HPV16 E6, Tip-1 and ARHGEF16 may cooperate to activate Cdc42 and support a potential link between the expression of HPV16 E6 and Cdc42 activation PMID: 21139582
    3. The ephexin4 protein mediates cell migration through a RhoG-dependent mechanism. PMID: 20679435
  • 亚细胞定位：
    Cytoplasm.
  • 数据库链接：

    HGNC: 15515

    KEGG: hsa:27237

    STRING: 9606.ENSP00000367629

    UniGene: Hs.87435