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ARL8A Antibody

  • 货号：
    CSB-PA919511
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA919511(ARL8A Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA919511(ARL8A Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

产品详情

  • Uniprot No.：
    Q96BM9
  • 基因名：
    ARL8A
  • 别名：
    ARL8A antibody; ARL10B antibody; GIE2ADP-ribosylation factor-like protein 8A antibody; ADP-ribosylation factor-like protein 10B antibody; Novel small G protein indispensable for equal chromosome segregation 2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human ARL8A
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:25-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plays a role in lysosome motility. In neurons, mediates the anterograde axonal long-range transport of presynaptic lysosome-related vesicles required for presynaptic biogenesis and synaptic function. May play a role in chromosome segregation.
  • 基因功能参考文献：
    1. Overexpression of Arl8a or Arl8b results in a microtubule-dependent redistribution of lysosomes towards the cell periphery. Live cell imaging suggested a role for Arl8a and Arl8b as positive regulators of lysosomal transport.[Ar18a] [Ar18b] PMID: 16537643
  • 亚细胞定位：
    Late endosome membrane. Lysosome membrane. Cytoplasm, cytoskeleton, spindle. Cell projection, axon. Cell junction, synapse.
  • 蛋白家族：
    Small GTPase superfamily, Arf family
  • 组织特异性：
    Ubiquitously expressed.
  • 数据库链接：

    HGNC: 25192

    OMIM: 616597

    KEGG: hsa:127829

    STRING: 9606.ENSP00000272217

    UniGene: Hs.497399