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ASIC5 Antibody

  • 货号：
    CSB-PA865174ESR2HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA865174ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA865174ESR2HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) ASIC5 Polyclonal antibody
  • Uniprot No.：
    Q9NY37
  • 基因名：
    ASIC5
  • 别名：
    Acid-sensing ion channel 5 antibody; amiloride sensitive cation channel 5, intestinal antibody; Amiloride sensitive sodium channel antibody; Amiloride-sensitive cation channel 5 antibody; ASIC5 antibody; ASIC5_HUMAN antibody; HINaC antibody; Human intestine Na(+) channel antibody; INAC antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Acid-sensing ion channel 5 protein (140-330AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Cation channel that gives rise to very low constitutive currents in the absence of activation. The activated channel exhibits selectivity for sodium, and is inhibited by amiloride.
  • 基因功能参考文献：
    1. hBASIC shares further key features with its rat ortholog: it is blocked by extracellular divalent cations, is inhibited by micromolar concentrations of the diarylamidine diminazene, and activated by millimolar concentrations of flufenamic acid. PMID: 23842738
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Amiloride-sensitive sodium channel (TC 1.A.6) family, ASIC5 subfamily
  • 组织特异性：
    Detected in small intestine, duodenum and jejunum. Detected at very low levels in testis and rectum.
  • 数据库链接：

    HGNC: 17537

    OMIM: 616693

    KEGG: hsa:51802

    STRING: 9606.ENSP00000442477

    UniGene: Hs.381349