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ASPRV1 Antibody

  • 中文名称：
    ASPRV1兔多克隆抗体
  • 货号：
    CSB-PA002231GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q53RT3
  • 基因名：
    ASPRV1
  • 别名：
    ASPRV1; SASP; Retroviral-like aspartic protease 1; Skin-specific retroviral-like aspartic protease; SASPase; Skin aspartic protease; TPA-inducible aspartic proteinase-like protein; TAPS
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human ASPRV1
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Protease responsible for filaggrin processing, essential for the maintenance of a proper epidermis organization.
  • 基因功能参考文献：
    1. results failed to find an association between ASPRV1 gene mutations and atopic eczema or clinically dry skin in the European populations studied PMID: 22318384
    2. SASPase activity is indispensable for processing profilaggrin and maintaining the texture and hydration of the stratum corneum. PMID: 21542132
    3. Identification and characterization of a new member of the aspartic proteases family, a unique epidermal retroviral-like protease, Skin ASpartic Protease. PMID: 16098038
    4. Taps expression is negatively associated with dedifferentiation and malignant progression in squamous cell carcinomas of the skin. PMID: 16565508
  • 亚细胞定位：
    Membrane; Single-pass membrane protein.
  • 组织特异性：
    Expressed primarily in the granular layer of the epidermis and inner root sheath of hair follicles. In psoriatic skin, expressed throughout the stratum corneum. In ulcerated skin, expressed in the stratum granulosum of intact epidermis but almost absent f
  • 数据库链接：

    HGNC: 26321

    OMIM: 611765

    KEGG: hsa:151516

    STRING: 9606.ENSP00000315383

    UniGene: Hs.516253