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ASUN Antibody

  • 货号：
    CSB-PA003054GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9NVM9
  • 基因名：
    INTS13
  • 别名：
    asun antibody; ASUN_HUMAN antibody; Cell cycle regulator Mat89Bb homolog antibody; Chromosome 12 open reading frame 11 antibody; FLJ10630 antibody; FLJ10637 antibody; Germ cell tumor 1 antibody; NET48 antibody; Protein asunder homolog antibody; Sarcoma antigen NY SAR 95 antibody; Sarcoma antigen NY-SAR-95 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human C12orf11
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Crucial regulator of the mitotic cell cycle and development. At prophase, required for dynein anchoring to the nuclear envelope important for proper centrosome-nucleus coupling. At G2/M phase, may be required for proper spindle formation and execution of cytokinesis. Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.
  • 基因功能参考文献：
    1. ASUN is identified as a functional component of Integrator (INT), a multisubunit complex required for 3'-end processing of small nuclear RNAs. PMID: 23904267
    2. Data suggest that ASUN promotes perinuclear enrichment of dynein at G2/M that facilitates BICD2- and CENP-F-mediated anchoring of dynein to nuclear pore complexes. PMID: 23097494
  • 亚细胞定位：
    Nucleus. Cytoplasm.
  • 蛋白家族：
    Asunder family
  • 组织特异性：
    Widely expressed. Tends to be up-regulated in seminomas compared to normal testis.
  • 数据库链接：

    HGNC: 20174

    OMIM: 615079

    KEGG: hsa:55726

    STRING: 9606.ENSP00000261191

    UniGene: Hs.505077