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ATG101 Antibody

  • 货号:
    CSB-PA883590LA01HU
  • 规格:
    ¥440
  • 促销:
    小规格抗体限时一口价
  • 图片:
    • Immunofluorescence staining of A549 cells with CSB-PA883590LA01HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他:

产品详情

  • 产品名称:
    Rabbit anti-Homo sapiens (Human) ATG101 Polyclonal antibody
  • Uniprot No.:
    Q9BSB4
  • 基因名:
  • 别名:
    ATG101 antibody; Atg13-interacting protein antibody; ATGA1_HUMAN antibody; Autophagy-related protein 101 antibody; C12orf44 antibody; Chromosome 12 open reading frame 44 antibody; FLJ11773 antibody; OTTHUMP00000241687 antibody; OTTHUMP00000241688 antibody; OTTHUMP00000241689 antibody
  • 宿主:
    Rabbit
  • 反应种属:
    Human
  • 免疫原:
    Recombinant Human Autophagy-related protein 101 protein (1-218AA)
  • 免疫原种属:
    Homo sapiens (Human)
  • 标记方式:
    Non-conjugated

    本页面中的产品,ATG101 Antibody (CSB-PA883590LA01HU),的标记方式是Non-conjugated。对于ATG101 Antibody,我们还提供其他标记。见下表:

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA883590LB01HU ATG101 Antibody, HRP conjugated ELISA
    FITC CSB-PA883590LC01HU ATG101 Antibody, FITC conjugated
    Biotin CSB-PA883590LD01HU ATG101 Antibody, Biotin conjugated ELISA
  • 克隆类型:
    Polyclonal
  • 抗体亚型:
    IgG
  • 纯化方式:
    Antigen Affinity Purified
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式:
    Liquid
  • 应用范围:
    ELISA, IF
  • 推荐稀释比:
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols:
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能:
    Autophagy factor required for autophagosome formation. Stabilizes ATG13, protecting it from proteasomal degradation.
  • 基因功能参考文献:
    1. Structure of the human Atg13-Atg101 HORMA heterodimer in the ULK1 complex that controls autophagy has been described. PMID: 26299944
    2. Data indicate mitogen lacritin stimulates FOXO3-ATG101 and FOXO1-ATG7 autophagic coupling and restores metabolic homeostasis. PMID: 23640897
    3. The identification of the novel protein, Atg101, and the validation of Atg13 and Atg101 as ULK1-interacting proteins, suggests an Atg1 complex is involved in the induction of macroautophagy in mammalian cells. PMID: 19287211
    4. These data suggest that Atg101 is a novel Atg protein that functions together with ULK, Atg13 and FIP200. PMID: 19597335
  • 亚细胞定位:
    Cytoplasm. Preautophagosomal structure.
  • 蛋白家族:
    ATG101 family
  • 数据库链接:

    HGNC: 25679

    OMIM: 615089

    KEGG: hsa:60673

    STRING: 9606.ENSP00000338990

    UniGene: Hs.9911