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ATG13 Antibody

  • 货号：
    CSB-PA560481
  • 规格：
    ￥880
  • 图片：
    • Immunohistochemical analysis of paraffin-embedded Human Skeletal Muscle Tissue using ATG13 Rabbit pAb diluted at 1:200
    • Immunohistochemical analysis of paraffin-embedded Human Brain Tissue using ATG13 Rabbit pAb diluted at 1:200
  • 其他：

产品详情

  • Uniprot No.：
    O75143
  • 基因名：
  • 别名：
    ATG13 antibody; ATG13 autophagy related 13 homolog (S. cerevisiae) antibody; ATG13_HUMAN antibody; Autophagy related 13 antibody; Autophagy related protein 13 antibody; Autophagy-related protein 13 antibody; FLJ20698 antibody; KIAA0652 antibody; OTTHUMP00000233321 antibody; OTTHUMP00000233322 antibody; OTTHUMP00000233323 antibody; OTTHUMP00000233324 antibody; OTTHUMP00000233325 antibody; OTTHUMP00000233326 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Recombinant Protein
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 纯化方式：
    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
  • 产品提供形式：
    Liquid
  • 应用范围：
    IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:50-1:200
    ELISA 1:10000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.
  • 基因功能参考文献：
    1. Specific affinity of the LC3 isoforms to the Atg13 LC3-interacting region is required for proper autophagosome formation. PMID: 24290141
    2. These data suggest that Atg101 is a novel Atg protein that functions together with ULK, Atg13 and FIP200. PMID: 19597335
    3. The gene product is the functional homologue of yeast Atg13, and required for autophagy in mammalian cells. PMID: 18936157
  • 亚细胞定位：
    Cytoplasm, cytosol. Preautophagosomal structure.
  • 蛋白家族：
    ATG13 family, Metazoan subfamily
  • 数据库链接：

    HGNC: 29091

    OMIM: 615088

    KEGG: hsa:9776

    UniGene: Hs.127403