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ATG13 Antibody

  • 货号：
    CSB-PA012203LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA012203LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA012203LA01HU at dilution of 1:100
    • Western Blot
      Positive WB detected in: A549 whole cell lysate
      All lanes: ATG13 antibody at 4µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 57, 53, 45, 61 kDa
      Observed band size: 57 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) ATG13 Polyclonal antibody
  • Uniprot No.：
    O75143
  • 基因名：
  • 别名：
    ATG13 antibody; ATG13 autophagy related 13 homolog (S. cerevisiae) antibody; ATG13_HUMAN antibody; Autophagy related 13 antibody; Autophagy related protein 13 antibody; Autophagy-related protein 13 antibody; FLJ20698 antibody; KIAA0652 antibody; OTTHUMP00000233321 antibody; OTTHUMP00000233322 antibody; OTTHUMP00000233323 antibody; OTTHUMP00000233324 antibody; OTTHUMP00000233325 antibody; OTTHUMP00000233326 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Autophagy-related protein 13 protein (315-517AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，ATG13 Antibody (CSB-PA012203LA01HU)，的标记方式是Non-conjugated。对于ATG13 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA012203LB01HU ATG13 Antibody, HRP conjugated ELISA
    FITC CSB-PA012203LC01HU ATG13 Antibody, FITC conjugated
    Biotin CSB-PA012203LD01HU ATG13 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.
  • 基因功能参考文献：
    1. Specific affinity of the LC3 isoforms to the Atg13 LC3-interacting region is required for proper autophagosome formation. PMID: 24290141
    2. These data suggest that Atg101 is a novel Atg protein that functions together with ULK, Atg13 and FIP200. PMID: 19597335
    3. The gene product is the functional homologue of yeast Atg13, and required for autophagy in mammalian cells. PMID: 18936157
  • 亚细胞定位：
    Cytoplasm, cytosol. Preautophagosomal structure.
  • 蛋白家族：
    ATG13 family, Metazoan subfamily
  • 数据库链接：

    HGNC: 29091

    OMIM: 615088

    KEGG: hsa:9776

    UniGene: Hs.127403