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ATP5F1 Antibody

  • 货号：
    CSB-PA020295
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of 3T3 cells using ATP5F1 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    P24539
  • 基因名：
  • 别名：
    AT5F1_HUMAN antibody; ATP synthase B chain mitochondrial antibody; ATP synthase subunit b antibody; ATP synthase subunit b mitochondrial antibody; ATP synthase; H+ transporting; mitochondrial F0 complex; subunit b; antibody; ATP synthase; H+ transporting; mitochondrial F0 complex; subunit b; isoform 1 antibody; ATP synthase; H+ transporting; mitochondrial F0 complex; subunit B1 antibody; ATP5F1 antibody; ATPase subunit b antibody; Cell proliferation inducing protein 47 antibody; H+ ATP synthase subunit b antibody; MGC24431 antibody; mitochondrial antibody; PIG47 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human ATP5F1.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:10000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
  • 基因功能参考文献：
    1. Down-regulation of mitochondrial ATPase by hypermethylation mechanism in chronic myeloid leukemia is associated with multidrug resistance. PMID: 20038517
    2. Nitration of tyrosine residues 368 and 345 in the beta-subunit elicits FoF1-ATPase activity loss. PMID: 19650768
  • 亚细胞定位：
    Mitochondrion. Mitochondrion inner membrane.
  • 蛋白家族：
    Eukaryotic ATPase B chain family
  • 数据库链接：

    HGNC: 840

    OMIM: 603270

    KEGG: hsa:515

    STRING: 9606.ENSP00000358737

    UniGene: Hs.514870