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ATP5L Antibody

  • 货号：
    CSB-PA002374LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • IHC image of CSB-PA002374LA01HU diluted at 1:600 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) ATP5L Polyclonal antibody
  • Uniprot No.：
    O75964
  • 基因名：
  • 别名：
    ATP synthase subunit g antibody; ATP synthase; H+ transporting; mitochondrial F1F0; subunit g antibody; ATP synthase; H+ transporting; mitochondrial Fo complex; subunit G antibody; ATP5L antibody; ATP5L_HUMAN antibody; ATPase subunit g antibody; F1Fo ATP synthase complex Fo membrane domain g subunit antibody; mitochondrial antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human ATP synthase subunit g, mitochondrial protein (2-103AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，ATP5L Antibody (CSB-PA002374LA01HU)，的标记方式是Non-conjugated。对于ATP5L Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA002374LB01HU ATP5L Antibody, HRP conjugated ELISA
    FITC CSB-PA002374LC01HU ATP5L Antibody, FITC conjugated
    Biotin CSB-PA002374LD01HU ATP5L Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:500-1:1000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
  • 基因功能参考文献：
    1. this study demonstrates that F1Fo ATP synthase can support general mitochondrial and cellular functions, working in extremely efficient 'energy saving' reverse mode and flexibly recruiting free radical detoxication and ATP producing / transporting pathways. PMID: 28189850
    2. Overexpression of miR-570-3p in platelets resulted in reduced levels of ATP5L mRNA and concomitant ATP loss. PMID: 27561077
  • 亚细胞定位：
    Mitochondrion. Mitochondrion inner membrane.
  • 蛋白家族：
    ATPase g subunit family
  • 数据库链接：

    HGNC: 14247

    OMIM: 617473

    KEGG: hsa:10632

    STRING: 9606.ENSP00000300688

    UniGene: Hs.486360