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ATP9A Antibody

  • 货号：
    CSB-PA002422LA01HU
  • 规格：
    ￥880
  • 图片：
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA002422LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA002422LA01HU at dilution of 1:100
    • Immunofluorescent analysis of Hela cells using CSB-PA002422LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) ATP9A Polyclonal antibody
  • Uniprot No.：
    O75110
  • 基因名：
    ATP9A
  • 别名：
    ATP 9A antibody; Atp9a antibody; ATP9A_HUMAN antibody; ATPase class II type 9A antibody; ATPase IIA antibody; ATPase type IV phospholipid transporting (P type) antibody; ATPase type IV phospholipid transporting (P type)(putative) antibody; ATPIIA antibody; KIAA0611 antibody; Phospholipid transporting ATPase IIA antibody; Probable phospholipid transporting ATPase IIA antibody; Probable phospholipid-transporting ATPase IIA antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Probable phospholipid-transporting ATPase IIA protein (2-69AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，ATP9A Antibody (CSB-PA002422LA01HU)，的标记方式是Non-conjugated。对于ATP9A Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA002422LB01HU ATP9A Antibody, HRP conjugated ELISA
    FITC CSB-PA002422LC01HU ATP9A Antibody, FITC conjugated
    Biotin CSB-PA002422LD01HU ATP9A Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plays a role in regulating membrane trafficking of cargo proteins, namely endosome to plasma membrane recycling and endosome to trans-Golgi network retrograde transport. In complex with MON2 and DOP1B, regulates SNX3 retromer-mediated endosomal sorting of WLS, a transporter of Wnt morphogens in developing tissues. Participates in the formation of endosomal carriers that direct WLS trafficking back to Golgi, away from lysosomal degradation. Appears to be implicated in intercellular communication by negatively regulating the release of exosomes. The flippase activity towards membrane lipids and its role in membrane asymmetry remains to be proved.
  • 基因功能参考文献：
    1. the predominant P4 ATPases in pure pancreatic beta cells and human and rat pancreatic islets were ATP8B1, ATP8B2, and ATP9A. ATP8B1 and CDC50A were highly concentrated in ISG PMID: 26240149
    2. Clinical trial and genome-wide association study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) PMID: 18519826
  • 亚细胞定位：
    Early endosome membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Cation transport ATPase (P-type) (TC 3.A.3) family, Type IV subfamily
  • 数据库链接：

    HGNC: 13540

    OMIM: 609126

    KEGG: hsa:10079

    STRING: 9606.ENSP00000342481

    UniGene: Hs.649234