Your Good Partner in Biology Research

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. Ace Antibody

Ace Antibody

  • 货号：
    CSB-PA001154XA01DLU
  • 规格：
    ￥880
  • 图片：
    • Western Blot
      Positive WB detected in: recombinant protein
      All lanes:Ace Antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 30 kDa
      Observed band size: 30 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Drosophila melanogaster (Fruit fly) Ace Antibody Polyclonal antibody
  • Uniprot No.：
    P07140
  • 基因名：
    Ace Antibody
  • 别名：
    Acetylcholinesterase (AChE) (EC 3.1.1.7) [Cleaved into: Acetylcholinesterase 16 kDa subunit; Acetylcholinesterase 55 kDa subunit] Ace CG17907
  • 宿主：
    Rabbit
  • 反应种属：
    Drosophila melanogaster (Fruit fly)
  • 免疫原：
    Recombinant Drosophila melanogaster (Fruit fly) Ace protein (44-293aa)
  • 免疫原种属：
    Drosophila melanogaster (Fruit fly)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Rapidly hydrolyzes choline released into the synapse. It can hydrolyze butyrylthiocholine.
  • 基因功能参考文献：
    1. 1 engineered disulfide bridge, I327C/D375C increased stability to heat denaturation, urea, & organic solvents & provided protease resistance. The new disulfide bridge links the N-terminal domain (first 356 aa) to the C-terminal domain. PMID: 16686937
    2. Results provide insights into substrate and product traffic in the Drosophila melanogaster acetylcholinesterase active site gorge. PMID: 18422651
    3. kinetic studies show that it affects interactions with peripheral ligands and the entrance of some of the bulkier substrates PMID: 18439026
    4. molecular dynamics simulation reveals the insecticidal resistance mechanism of AChE and its mutation PMID: 19263097
  • 亚细胞定位：
    Cell junction, synapse. Cell membrane; Lipid-anchor, GPI-anchor. Note=Attached to the membrane of the neuronal cholinergic synapses by a GPI-anchor.
  • 蛋白家族：
    Type-B carboxylesterase/lipase family
  • 数据库链接：

    KEGG: dme:Dmel_CG17907

    STRING: 7227.FBpp0289713

    UniGene: Dm.1179