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Alpha-conotoxin VxXXC Antibody

  • 货号：
    CSB-PA314942ZA01DWK
  • 规格：
    ￥880
  • 图片：
    • Western Blot
      Positive WB detected in: recombinant protein
      All lanes:Alpha-conotoxin VxXXC Antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 22 kDa
      Observed band size: 22 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Conus vexillum (Flag cone) Alpha-conotoxin VxXXC Antibody Polyclonal antibody
  • Uniprot No.：
    P0C1W7
  • 基因名：
    Alpha-conotoxin VxXXC Antibody
  • 别名：
    Alpha-conotoxin VxXXC (VxXIIC)
  • 宿主：
    Rabbit
  • 反应种属：
    Conus vexillum (Flag cone)
  • 免疫原：
    Recombinant Conus vexillum (Flag cone) Alpha-conotoxin VxXXC protein (1-47aa)
  • 免疫原种属：
    Conus vexillum (Flag cone)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This toxin specifically blocks mammalian neuronal nAChR of the alpha-7/CHRNA7, alpha-3-beta-2/CHRNA3-CHRNB2 and alpha-4-beta-2/CHRNA4-CHRNB2 subtypes. VxXXA and VxXXB inhibit alpha-7/CHRNA7 and alpha-3-beta-2/CHRNA3-CHRNB2 nAChR more efficiently than VxXXC. VxXXB is the most effective at inhibiting alpha-4-beta-2/CHRNA4-CHRNB2 nAChR, followed by VxXXC and VxXXA.
  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Conotoxin D superfamily
  • 组织特异性：
    Expressed by the venom duct.