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B3GALT4 Antibody

  • 中文名称：
    B3GALT4兔多克隆抗体
  • 货号：
    CSB-PA002492LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: U87 whole cell lysate, A549 whole cell lysate, Mouse skeletal muscle tissue
      All lanes: B3GALT4 antibody at 3µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 42 kDa
      Observed band size: 42 kDa
    • Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA002492LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA002492LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) B3GALT4 Polyclonal antibody
  • Uniprot No.：
    O96024
  • 基因名：
    B3GALT4
  • 别名：
    B3GALT4; GALT4; Beta-1,3-galactosyltransferase 4; Beta-1,3-GalTase 4; Beta3Gal-T4; Beta3GalT4; GalT4; b3Gal-T4; Gal-T2; Ganglioside galactosyltransferase; UDP-galactose:beta-N-acetyl-galactosamine-beta-1,3-galactosyltransferase
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Beta-1,3-galactosyltransferase 4 protein (42-266AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，B3GALT4 Antibody (CSB-PA002492LA01HU)，的标记方式是Non-conjugated。对于B3GALT4 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA002492LB01HU B3GALT4 Antibody, HRP conjugated ELISA
    FITC CSB-PA002492LC01HU B3GALT4 Antibody, FITC conjugated
    Biotin CSB-PA002492LD01HU B3GALT4 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in GM1/GD1B/GA1 ganglioside biosynthesis.
  • 基因功能参考文献：
    1. Colorectal cancer (CRC) patients expressing both high B7-H3 and high B3GALT4 contributed to a significant decrease in overall survival. The expression of B3GALT4 in CRC is positively correlated with B7-H3 expression in vitro. B7-H3/B3GLAT4 may be used as dual prognostic biomarkers for CRC. PMID: 30131660
    2. Induction of GM1a/GD1b synthase triggers complex ganglioside expression and alters neuroblastoma cell behavior; a new tumor cell model of ganglioside function PMID: 21519903
    3. Data showed that GM1/GD1b/GA1 synthase transfectant cells had definite reduction in cell growth and invasion. PMID: 20594196
    4. We found beta3Gal-T4 and T5 enzymatic activity in ovarian cancer tissues, indicating that these enzymes are expressed at least in ovarian cancer PMID: 19225246
  • 亚细胞定位：
    Golgi apparatus membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Glycosyltransferase 31 family
  • 组织特异性：
    Highly expressed in heart, skeletal muscle and pancreas and, to a lesser extent, in brain, placenta, kidney, liver and lung.
  • 数据库链接：

    HGNC: 919

    OMIM: 603095

    KEGG: hsa:8705

    STRING: 9606.ENSP00000390784

    UniGene: Hs.534375