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B3GNT2 Antibody

  • 货号：
    CSB-PA002500LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: B3GNT2 antibody at 4µg/ml
      Lane 1: 293T whole cell lysate
      Lane 2: Jurkat whole cell lysate
      Lane 3: HL60 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 47, 46 kDa
      Observed band size: 47 kDa
    • Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA002500LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) B3GNT2 Polyclonal antibody
  • Uniprot No.：
    Q9NY97
  • 基因名：
    B3GNT2
  • 别名：
    3-galactosyltransferase 7 antibody; 3-GalTase 7 antibody; 3-Gn-T1 antibody; 3-Gn-T2 antibody; 3-N-acetylglucosaminyltransferase 1 antibody; 3-N-acetylglucosaminyltransferase 2 antibody; b3Gal-T7 antibody; B3GN2_HUMAN antibody; B3GNT antibody; B3GNT2 antibody; Beta 1 3 galactosyltransferase 7 antibody; Beta-1 antibody; Beta-3-Gx-T7 antibody; Beta3Gal-T7 antibody; Beta3GalT7 antibody; Beta3Gn T1 antibody; Beta3Gn-T1 antibody; Beta3Gn-T2 antibody; Beta3GNT antibody; BGnT-1 antibody; BGnT-2 antibody; UDP-Gal:beta-GlcNAc beta-1 antibody; UDP-galactose:beta-N-acetylglucosamine beta-1 antibody; UDP-GlcNAc:betaGal beta-1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 protein (29-397AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，B3GNT2 Antibody (CSB-PA002500LA01HU)，的标记方式是Non-conjugated。对于B3GNT2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA002500LB01HU B3GNT2 Antibody, HRP conjugated ELISA
    FITC CSB-PA002500LC01HU B3GNT2 Antibody, FITC conjugated
    Biotin CSB-PA002500LD01HU B3GNT2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Beta-1,3-N-acetylglucosaminyltransferase involved in the synthesis of poly-N-acetyllactosamine. Catalyzes the initiation and elongation of poly-N-acetyllactosamine chains. Shows a marked preference for Gal(beta1-4)Glc(NAc)-based acceptors. Probably constitutes the main polylactosamine synthase.
  • 基因功能参考文献：
    1. we confirmed the involvement of BGNT-1.1 in ciliated sensory neuron function and morphogenesis. BGNT-1.1 functions at the trans-Golgi network of sheath cells (glia) to influence dye-filling and cilium length, in a cell non-autonomous manner. Notably, BGNT-1.1 is the orthologue of human B3GNT1/B4GAT1, a glycosyltransferase associated with Walker-Warburg syndrome (WWS). PMID: 27508411
    2. High B3GNT2 expression is associated with hepatocellular carcinoma. PMID: 25605193
    3. data reveals beta3GnT2 and polyLacNAc may be involved in the progression of the pre-malignant lesions of human the uterine cervix. PMID: 24998922
    4. beta3Gal-T5, controlled by the intestinal homeoproteins, may play an important role in the specific function of intestinal cells by modifying the carbohydrate structure of glycoproteins PMID: 12855703
    5. beta3Gal-T5 is presumed to be responsible for the synthesis of CA 19-9 in pancreatic cancer tissue. PMID: 14555842
    6. beta 3Gal-T5 plays a relevant role in gastrointestinal and pancreatic tissues counteracting the glycosylation pattern associated with malignancy PMID: 14686931
    7. beta1, 3-N-acetylglucosaminyltransferase is similar to a new protein, beta3-GnTL1 PMID: 15560372
    8. up-regulation of beta3Gn-T8 in differentiated cells increases poly-N-acetyllactosamine chains by activating intrinsic beta3Gn-T2. PMID: 18826941

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  • 亚细胞定位：
    Golgi apparatus membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Glycosyltransferase 31 family
  • 组织特异性：
    Ubiquitous.
  • 数据库链接：

    HGNC: 15629

    OMIM: 605581

    KEGG: hsa:10678

    STRING: 9606.ENSP00000305595

    UniGene: Hs.173203