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BBC3 Antibody

  • 货号：
    CSB-PA620085
  • 规格：
    ￥1100
  • 图片：
    • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: A549 cells, Primary antibody: CSB-PA620085(BBC3 Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes
  • 其他：

产品详情

  • Uniprot No.：
    Q9BXH1
  • 基因名：
  • 别名：
    BBC 3 antibody; Bbc3 antibody; BBC3_HUMAN antibody; BCL 2 binding component 3 antibody; Bcl-2-binding component 3 antibody; BCL2 binding component 3 antibody; JFY 1 antibody; JFY-1 antibody; JFY1 antibody; p53 up regulated modulator of apoptosis antibody; p53 up-regulated modulator of apoptosis antibody; p53 Upregulated Modulator of Apoptosis antibody; PUMA alpha antibody; PUMA/JFY1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthetic peptide of Human BBC3
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis. Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis.
  • 亚细胞定位：
    Mitochondrion. Note=Localized to the mitochondria in order to induce cytochrome c release.
  • 蛋白家族：
    Bcl-2 family
  • 组织特异性：
    Ubiquitously expressed.
  • 数据库链接：

    HGNC: 17868

    OMIM: 605854

    KEGG: hsa:27113

    UniGene: Hs.467020