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BIN2 Antibody

  • 货号：
    CSB-PA002701GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9UBW5
  • 基因名：
    BIN2
  • 别名：
    BIN2 antibody; BRAP1Bridging integrator 2 antibody; Breast cancer-associated protein 1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Human BIN2
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Promotes cell motility and migration, probably via its interaction with the cell membrane and with podosome proteins that mediate interaction with the cytoskeleton. Modulates membrane curvature and mediates membrane tubulation. Plays a role in podosome formation. Inhibits phagocytosis.
  • 基因功能参考文献：
    1. Bin2 is a membrane-sculpting protein that influences podosome formation, motility and phagocytosis in leucocytes. PMID: 23285027
    2. Bin2 is a BAR domain adapter protein structurally related but functionally distinct from family members Bin1 and amphiphysin. PMID: 10903846
  • 亚细胞定位：
    Cytoplasm. Cell projection, podosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cell cortex. Cell projection, phagocytic cup.
  • 组织特异性：
    Detected in natural killer cells (at protein level). Highest level expression seen in spleen and peripheral blood leukocytes and is also expressed at high levels in thymus, colon and placenta, suggesting preferential expression in hematopoietic tissues.
  • 数据库链接：

    HGNC: 1053

    OMIM: 605936

    KEGG: hsa:51411

    STRING: 9606.ENSP00000267012

    UniGene: Hs.14770