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BIN3 Antibody

  • 货号：
    CSB-PA986283
  • 规格：
    ￥1100
  • 图片：
    • Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-4: 231 cells, A549 cells, LoVo cells, HepG2 cells, Primary antibody: CSB-PA986283(BIN3 Antibody) at dilution 1/225, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
  • 其他：

产品详情

  • Uniprot No.：
    Q9NQY0
  • 基因名：
    BIN3
  • 别名：
    BIN3Bridging integrator 3 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human BIN3
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in cytokinesis and septation where it has a role in the localization of F-actin.
  • 基因功能参考文献：
    1. like RVS161, hob3+ and BIN3 regulate F-actin localization, but other roles for these genes have diverged somewhat during evolution PMID: 11274158
    2. BIN3 is a BAR domain adapter protein implicated in actin regulation; it is homologous to budding yeast Rvs161 and fission yeast Hob3. PMID: 11274158
  • 亚细胞定位：
    Cytoplasm, cytoskeleton.
  • 组织特异性：
    Ubiquitously expressed except in brain.
  • 数据库链接：

    HGNC: 1054

    OMIM: 606396

    KEGG: hsa:55909

    STRING: 9606.ENSP00000276416

    UniGene: Hs.433722