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BIRC8 Antibody

  • 货号：
    CSB-PA846680ESR2HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) BIRC8 Polyclonal antibody
  • Uniprot No.：
    Q96P09
  • 基因名：
  • 别名：
    Baculoviral IAP repeat containing 8 antibody; Baculoviral IAP repeat containing protein 8 antibody; Baculoviral IAP repeat-containing protein 8 antibody; BIRC 8 antibody; BIRC8 antibody; BIRC8 protein antibody; BIRC8_HUMAN antibody; hILP 2 antibody; hILP2 antibody; IAP like protein 2 antibody; IAP-like protein 2 antibody; ILP 2 antibody; ILP-2 antibody; Inhibitor of apoptosis like protein 2 antibody; Inhibitor of apoptosis-like protein 2 antibody; Testis specific inhibitor of apoptosis antibody; Testis-specific inhibitor of apoptosis antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Baculoviral IAP repeat-containing protein 8 protein (1-236AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Protects against apoptosis mediated by BAX.
  • 基因功能参考文献：
    1. High ILP-2 expression is associated with breast cancer. PMID: 30106449
    2. Fumonisin B1 caused dose-dependent increase in BIRC-8/ILP-2 mRNA and protein expression in HepG2 cells to inhibit apoptosis. PMID: 25800559
    3. results indicate that ILP-2 is a novel breast cancer biomarker in the peripheral blood. PMID: 23222679
    4. increased expression with progression of chronic myeloid leukaemia PMID: 24266799
    5. role in preventing shear-stress induced endothelial cell apoptosis via negative regulation of caspase-3 PMID: 12372615
    6. ILP2 is an unstable protein, and cannot inhibit caspase 9 in a physiological way on its own; possibly ILP2 requires assistance from unidentified cellular factors to be an effective inhibitor of apoptosis in vivo PMID: 15485395

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  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    IAP family
  • 组织特异性：
    Testis specific in normal tissues.
  • 数据库链接：

    HGNC: 14878

    KEGG: hsa:112401

    STRING: 9606.ENSP00000412957

    UniGene: Hs.348263