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BLLF1 Antibody

  • 货号：
    CSB-PA360986LA01EFA
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Epstein-Barr virus BLLF1 Polyclonal antibody
  • Uniprot No.：
    P03200
  • 基因名：
    BLLF1
  • 别名：
    BLLF1 antibody; Envelope glycoprotein GP350 antibody; Membrane antigen antibody; MA antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Epstein-Barr virus
  • 免疫原：
    Recombinant Epstein-Barr virus Envelope glycoprotein GP350 protein (1-493AA)
  • 免疫原种属：
    Epstein-Barr virus
  • 标记方式：
    Non-conjugated

    本页面中的产品，BLLF1 Antibody (CSB-PA360986LA01EFA)，的标记方式是Non-conjugated。对于BLLF1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA360986LB01EFA BLLF1 Antibody, HRP conjugated ELISA
    FITC CSB-PA360986LC01EFA BLLF1 Antibody, FITC conjugated
    Biotin CSB-PA360986LD01EFA BLLF1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Initiates virion attachment to host B-lymphocyte cell, leading to virus entry. Acts by binding to host CR2 at the surface of B-lymphocytes, facilitating the binding of viral glycoprotein gp42 to HLA class II molecules. Attachment triggers virion-host membrane fusion and invasion of the host cell.
  • 基因功能参考文献：
    1. The similar distribution of gp350/220 variants in nasopharyngeal carcinoma, EBV-associated gastric carcinoma and healthy donors suggest that gp350/220 variations are geographically restricted rather than tumor-specific polymorphisms. PMID: 22038027
    2. gp350 mainly exerts its functions after the internalization step, presumably during release of the viral capsid from the endosomal compartment, and that CD21-dependent but also CD21-independent molecular mechanisms are involved in this process. PMID: 19889766
    3. X-ray structure of the highly glycosylated gp350; defined the CR2 binding site on gp350, deglycosylated gp350 bound CR2 similarly to the glycosylated form, suggesting that glycosylation is not important for receptor binding PMID: 17072314
    4. These site-directed mutations identified a novel negatively charged complement receptor type 2-binding surface described by residues Glu-21, Asp-22, Glu-155, Asp-208, Glu-210, and Asp-296. PMID: 18786993
  • 亚细胞定位：
    Virion membrane; Single-pass membrane protein. Host membrane; Single-pass membrane protein. Note=Most abundant component of the viral envelope.
  • 蛋白家族：
    Epstein-Barr GP350 family
  • 数据库链接：

    KEGG: vg:3783713