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BRD9 Antibody

  • 货号：
    CSB-PA888000ESR2HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: Bromodomain-containing protein 9 antibody at 2μg/ml + Mouse liver tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 68, 23, 54, 27, 56, 61 kDa
      Observed band size: 68 kDa
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA888000ESR2HU at dilution of 1:100
    • Immunofluorescent analysis of HepG2 cells using CSB-PA888000ESR2HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品描述：

    A partial recombinant protein of the human BRD9 protein, corresponding to the 338-597 amino acids, was used to immunize the rabbit to synthesize the BRD9 antibody. The resulting BRD9 antibody is an unconjugated IgG isoform that has undergone antigen affinity purification.

    To ensure its reliability, this BRD9 polyclonal antibody has been rigorously quality controlled in multiple applications, including ELISA, WB, IHC, and IF. It has been shown to be reactive with human and mouse BRD9 proteins. The BRD9 protein is a subunit of the BAF chromatin remodeling complex, which plays a crucial role in regulating gene expression and chromatin structure. Additionally, BRD9 has been implicated in other cellular processes, such as cell division, DNA damage repair, and cell differentiation.

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) BRD9 Polyclonal antibody
  • Uniprot No.：
    Q9H8M2
  • 基因名：
  • 别名：
    BRD9 antibody; UNQ3040/PRO9856Bromodomain-containing protein 9 antibody; Rhabdomyosarcoma antigen MU-RMS-40.8 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Bromodomain-containing protein 9 protein (338-597AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:200-1:1000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plays a role in chromatin remodeling and regulation of transcription. Acts as a chromatin reader that recognizes and binds acylated histones: binds histones that are acetylated and/or butyrylated. Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Orchestrates also the RAD51-RAD54 complex formation and thereby plays a role in homologous recombination (HR).
  • 基因功能参考文献：
    1. The bromodomains of BRD9, CECR2, and the second bromodomain of TAF1 recognize the longer butyryl mark on histones. In addition, the TAF1 second bromodomain is capable of binding crotonyl marks. PMID: 26365797
  • 数据库链接：

    HGNC: 25818

    KEGG: hsa:65980

    STRING: 9606.ENSP00000419765

    UniGene: Hs.449278