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BTBD1 Antibody

  • 货号：
    CSB-PA002840GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9H0C5
  • 基因名：
    BTBD1
  • 别名：
    BTBD1 antibody; C15orf1 antibody; NS5ATP8BTB/POZ domain-containing protein 1 antibody; Hepatitis C virus NS5A-transactivated protein 8 antibody; HCV NS5A-transactivated protein 8 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human BTBD1
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Seems to regulate expression levels and/or subnuclear distribution of TOP1, via an unknown mechanism. May play a role in mesenchymal differentiation where it promotes myogenic differentiation and suppresses adipogenesis.
  • 基因功能参考文献：
    1. Interaction of BTBD1 and BTBD2 with TOP1 requires TOP1 residues 236 and 237, the same residues required to enhance the infectivity of progeny virions when TOP1 is expressed in African Green Monkey producer cells. PMID: 21092135
    2. subcellular colocalization of BTBD1 and BTBD2 to cytoplasmic bodies; TRIM5delta colocalized with BTBD1/2 and appeared to serve as a scaffold for the assembly of endogenous BTBD1/2 proteins PMID: 12878161
    3. BTBD1 is essential for myogenic differentiation PMID: 15486563
  • 亚细胞定位：
    Cytoplasm.
  • 组织特异性：
    Ubiquitous; highest levels in testes, heart and skeletal muscle.
  • 数据库链接：

    HGNC: 1120

    OMIM: 608530

    KEGG: hsa:53339

    STRING: 9606.ENSP00000261721

    UniGene: Hs.459149