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C8G Antibody

  • 货号：
    CSB-PA004196LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: C8G antibody at 2µg/ml + Human serum
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 23 kDa
      Observed band size: 23 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) C8G Polyclonal antibody
  • Uniprot No.：
    P07360
  • 基因名：
  • 别名：
    C8C antibody; C8G antibody; CO8G_HUMAN antibody; Complement component 8 gamma polypeptide antibody; Complement component C8 gamma chain antibody; MGC142186 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Complement component C8 gamma chain protein (21-202AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，C8G Antibody (CSB-PA004196LA01HU)，的标记方式是Non-conjugated。对于C8G Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA004196LB01HU C8G Antibody, HRP conjugated ELISA
    FITC CSB-PA004196LC01HU C8G Antibody, FITC conjugated
    Biotin CSB-PA004196LD01HU C8G Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    C8 is a constituent of the membrane attack complex. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol.
  • 基因功能参考文献：
    1. Binding of C8 gamma subunit to C8 beta is dependent on the thrombospondin type 1 module + low-density lipoprotein receptor class A module + membrane attack complex/perforin domain of C8 beta. PMID: 12220191
    2. structure of a C8gamma.laurate complex revealed Y83 and Y131 can move to allow penetration of hydrocarbon chain of laurate into the lower cavity. A Y83W mutation blocked access but had no effect on the ability of C8gamma to enhance C8 cytolytic activity PMID: 17452033
  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Calycin superfamily, Lipocalin family
  • 数据库链接：

    HGNC: 1354

    OMIM: 120930

    KEGG: hsa:733

    STRING: 9606.ENSP00000224181

    UniGene: Hs.1285