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C9orf89 Antibody

  • 货号：
    CSB-PA070012
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    Q96LW7
  • 基因名：
    CARD19
  • 别名：
    Bcl10 interacting protein with CARD protein antibody; Bcl10-interacting CARD protein antibody; BINCA_HUMAN antibody; BinCARD antibody; C9orf89 antibody; Chromosome 9 open reading frame 89 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human BinCARD.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B. May inhibit the phosphorylation of BCL10 in a CARD-dependent manner.
  • 基因功能参考文献：
    1. the crystal structure of BinCARD reveals that all three cysteines were oxidized PMID: 23633586
    2. BinCard inhibits BCL10-mediated activation of NF-kappa B. PMID: 15637807
  • 亚细胞定位：
    [Isoform 1]: Nucleus. Note=Coexpression with BCL10 induced translocation from nucleus to cytosol.; [Isoform 2]: Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein.
  • 组织特异性：
    Expressed in ovary, testis, placenta, skeletal muscle, kidney, lung, heart and liver (at protein level). Expressed in thymus and brain.
  • 数据库链接：

    HGNC: 28148

    OMIM: 617726

    KEGG: hsa:84270

    UniGene: Hs.434213