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CA5B Antibody

  • 货号：
    CSB-PA006799
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of 3T3 cells using CA VB Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q9Y2D0
  • 基因名：
    CA5B
  • 别名：
    CA VB antibody; CA-VB antibody; CA5B antibody; CAH5B_HUMAN antibody; Carbonate dehydratase VB antibody; Carbonic anhydrase 5B antibody; Carbonic anhydrase 5B; mitochondrial antibody; Carbonic anhydrase VB antibody; Carbonic anhydrase VB; mitochondrial antibody; mitochondrial antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human CA VB.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, IF, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:10000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Reversible hydration of carbon dioxide.
  • 基因功能参考文献：
    1. In 10 of 96 patients, mutations in CA5A were identified on both alleles but none in CA5B. Exhibiting decreased enzyme activity or thermal stability, all CAVA mutations were proven to cause disease, whereas the three variants showed no relevant effect PMID: 26913920
    2. activators enhanced kcat, with no effect on KM, favoring the RDS in the catalytic cycle; the activation pattern of the two mitochondrial isoforms is very different from each other and as compared to those of the cytosolic isoforms hCA I and II. PMID: 17174092
  • 亚细胞定位：
    Mitochondrion.
  • 蛋白家族：
    Alpha-carbonic anhydrase family
  • 组织特异性：
    Strongest expression in heart, pancreas, kidney, placenta, lung, and skeletal muscle. Not expressed in liver.
  • 数据库链接：

    HGNC: 1378

    OMIM: 300230

    KEGG: hsa:11238

    STRING: 9606.ENSP00000314099

    UniGene: Hs.653287