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CALCOCO1 Antibody

  • 货号：
    CSB-PA004436GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9P1Z2
  • 基因名：
    CALCOCO1
  • 别名：
    CALCOCO1 antibody; KIAA1536 antibody; PP13275 antibody; UNQ2436/PRO4996Calcium-binding and coiled-coil domain-containing protein 1 antibody; Calphoglin antibody; Coiled-coil coactivator protein antibody; Sarcoma antigen NY-SAR-3 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human CALCOCO1
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC,IF
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Functions as a coactivator for aryl hydrocarbon and nuclear receptors (NR). Recruited to promoters through its contact with the N-terminal basic helix-loop-helix-Per-Arnt-Sim (PAS) domain of transcription factors or coactivators, such as NCOA2. During ER-activation acts synergistically in combination with other NCOA2-binding proteins, such as EP300, CREBBP and CARM1. Involved in the transcriptional activation of target genes in the Wnt/CTNNB1 pathway. Functions as a secondary coactivator in LEF1-mediated transcriptional activation via its interaction with CTNNB1. Coactivator funct...显示更多
  • 基因功能参考文献：
    1. Results report a novel human protein, calphoglin, which activates inorganic pyrophosphatase (IPP) and enhances phosphoglucomutase activity through the activated IPP. PMID: 15522220
    2. CoCoA uses different combinations of functional domains in its synergistic coactivator function with beta-catenin or GRIP1 PMID: 16344550
    3. The N terminus of CoCoA contains another activation domain , which is necessary and sufficient for synergistic activation of LEF1-mediated transcription by CoCoA and beta-catenin. PMID: 16931570
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    CALCOCO family
  • 数据库链接：

    HGNC: 29306

    KEGG: hsa:57658

    STRING: 9606.ENSP00000449960

    UniGene: Hs.156667