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CARD17 Antibody

  • 货号：
    CSB-PA680389
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA680389(CARD17 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA680389(CARD17 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

产品详情

  • Uniprot No.：
    Q5XLA6
  • 基因名：
  • 别名：
    CAR17_HUMAN antibody; CARD 17 antibody; CARD17 antibody; Caspase 1 inhibitor antibody; Caspase recruitment domain containing protein 17 antibody; Caspase recruitment domain-containing protein 17 antibody; Caspase-1 inhibitor INCA antibody; Caspase1 inhibitor antibody; Inhibitory caspase recruitment domain (CARD) protein antibody; Inhibitory caspase recruitment domain protein antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthetic peptide of Human CARD17
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:5000
    IHC 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation.
  • 基因功能参考文献：
    1. INCA is a novel intracellular regulator of procaspase-1 activation, involved in the regulation of pro-IL-1beta processing and its release during inflammation PMID: 15383541
  • 亚细胞定位：
    Cytoplasm.
  • 组织特异性：
    Ubiquitous.
  • 数据库链接：

    HGNC: 33827

    OMIM: 609490

    KEGG: hsa:440068

    STRING: 9606.ENSP00000364859

    UniGene: Hs.732627