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CARF Antibody

  • 货号：
    CSB-PA000866
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of HuvEc cells using ALS2CR8 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q8N187
  • 基因名：
    CARF
  • 别名：
    Amyotrophic lateral sclerosis 2 (juvenile) chromosome region candidate 8 antibody; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein antibody; Calcium response factor antibody; Calcium-response factor antibody; Calcium-responsive transcription factor antibody; CaRF antibody; CARTF_HUMAN antibody; Testis development protein NYD SP24 antibody; Testis development protein NYD-SP24 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human ALS2CR8.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Acts as a transcriptional activator that mediates the calcium- and neuron-selective induction of BDNF exon III transcription. Binds to the consensus calcium-response element CaRE1 5'-CTATTTCGAG-3' sequence.
  • 基因功能参考文献：
    1. Data demonstrate that CARF is a new target of miR-451 that mediates its tumor suppressor function in normal and stressed biological states. PMID: 29321561
    2. Cloned as a calcium- and neural-selective transcriptional activator of the gene for Brain-Derived Neurotrophic Factor (BDNF). PMID: 11832226
  • 亚细胞定位：
    Nucleus.
  • 数据库链接：

    HGNC: 14435

    OMIM: 607586

    KEGG: hsa:79800

    STRING: 9606.ENSP00000316224

    UniGene: Hs.444982