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CCT6A Antibody

  • 货号：
    CSB-PA004865EA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: Hela whole cell lysate, HepG2 whole cell lysate, U251 whole cell lysate, 293T whole cell lysate
      All lanes: CCT6A antibody at 4.2µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 59, 54 kDa
      Observed band size: 54 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) CCT6A Polyclonal antibody
  • Uniprot No.：
    P40227
  • 基因名：
    CCT6A
  • 别名：
    CCT6A antibody; CCT6 antibody; CCTZ antibody; T-complex protein 1 subunit zeta antibody; TCP-1-zeta antibody; Acute morphine dependence-related protein 2 antibody; CCT-zeta-1 antibody; HTR3 antibody; Tcp20 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human T-complex protein 1 subunit zeta protein (80-250AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，CCT6A Antibody (CSB-PA004865EA01HU)，的标记方式是Non-conjugated。对于CCT6A Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA004865EB01HU CCT6A Antibody, HRP conjugated ELISA
    FITC CSB-PA004865EC01HU CCT6A Antibody, FITC conjugated
    Biotin CSB-PA004865ED01HU CCT6A Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. The TRiC complex plays a role in the folding of actin and tubulin (Probable).
  • 基因功能参考文献：
    1. High expression of CCT6A is associated with Non-Small Cell Lung Cancer. PMID: 28104536
    2. selective inhibition of SMAD3 or CCT6A efficiently suppresses TGF-beta-mediated metastasis. Findings provide a mechanism that directs TGF-beta signaling toward its prometastatic arm and may contribute to the development of therapeutic strategies targeting TGF-beta for non-small-cell lung carcinoma. PMID: 28375158
    3. These data suggest that CCT6A is a novel autoantigen recognized by Vdelta2 gammadelta T cells, which deepens our understanding of mechanisms in autoimmune diseases. PMID: 27489109
    4. identified genes, which include Tcp20, may play important role in conferring radioresistance to oral squamous cell carcinoma and could be useful in identifying cases with more radioresistance PMID: 16211299
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    TCP-1 chaperonin family
  • 数据库链接：

    HGNC: 1620

    OMIM: 104613

    KEGG: hsa:908

    STRING: 9606.ENSP00000275603

    UniGene: Hs.82916