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CD300LG Antibody

  • 货号：
    CSB-PA751016LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: Rat kidney tissue
      All lanes: CD300LG antibody at 6μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 37, 27, 25, 34, 30 kDa
      Observed band size: 37 kDa
    • Immunofluorescence staining of 293 cells with CSB-PA751016LA01HU at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
    • IHC image of CSB-PA751016LA01HU diluted at 1:200 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) CD300LG Polyclonal antibody
  • Uniprot No.：
    Q6UXG3
  • 基因名：
    CD300LG
  • 别名：
    CD300 antigen-like family member G antibody; CD300 molecule like family member g antibody; CD300g antibody; Cd300lg antibody; CLM-9 antibody; CLM9 antibody; CLM9_HUMAN antibody; CMRF35-like molecule 9 antibody; Nepmucin antibody; TREM-4 antibody; TREM4 antibody; Triggering receptor expressed on myeloid cells 4 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Rat
  • 免疫原：
    Recombinant Human CMRF35-like molecule 9 protein (128-241AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，CD300LG Antibody (CSB-PA751016LA01HU)，的标记方式是Non-conjugated。对于CD300LG Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA751016LB01HU CD300LG Antibody, HRP conjugated ELISA
    FITC CSB-PA751016LC01HU CD300LG Antibody, FITC conjugated
    Biotin CSB-PA751016LD01HU CD300LG Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:200-1:500
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Receptor which may mediate L-selectin-dependent lymphocyte rollings. Binds SELL in a calcium dependent manner. Binds lymphocyte.
  • 基因功能参考文献：
    1. Both mRNA and protein levels of CD300LG-g in pulmonary carcinoma tissues were significantly lower than that in tumor-adjacent tissues, which might lead to inhibition of killing function of immunocytes, resulting in immune escape of lung cancer cells. PMID: 26977771
    2. Blood pressure, measured with a sensitive method, in a small sample of CD300LG rs72836561 CT-carriers was higher than in CC-carriers. PMID: 25314291
  • 亚细胞定位：
    Apical cell membrane; Single-pass type I membrane protein. Basolateral cell membrane; Single-pass type I membrane protein. Endosome, multivesicular body membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    CD300 family
  • 组织特异性：
    Highly expressed in heart, skeletal muscle and placenta.
  • 数据库链接：

    HGNC: 30455

    OMIM: 610520

    KEGG: hsa:146894

    STRING: 9606.ENSP00000321005

    UniGene: Hs.147313