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  4. CD302 Antibody

CD302 Antibody

  • 货号：
    CSB-PA080099
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    Q8IX05
  • 基因名：
    CD302
  • 别名：
    BIMLEC antibody; C type lectin BIMLEC antibody; C type lectin domain family 13 member A antibody; C-type lectin BIMLEC antibody; C-type lectin domain family 13 member A antibody; CD302 antibody; CD302 antigen antibody; CD302_HUMAN antibody; CLEC13A antibody; DCL1 antibody; KIAA0022 antibody; Type I transmembrane C type lectin receptor DCL-1 antibody; Type I transmembrane C-type lectin receptor DCL-1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human DCL-1.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Potential multifunctional C-type lectin receptor that may play roles in endocytosis and phagocytosis as well as in cell adhesion and migration.
  • 基因功能参考文献：
    1. These studies confirm a functional role for CD302 in myeloid dendritic cells migration. PMID: 27316686
    2. Decreased DCL1 is associated with angiogenesis in prostate cancer. PMID: 20861185
    3. Hodgkin's lymphoma cell lines express a fusion protein encoded by intergenically spliced mRNA for the multilectin receptor DEC-205 (CD205) and a novel C-type lectin receptor DCL-1 PMID: 12824192
    4. hDCL-1 is an unconventional lectin receptor that plays roles not only in endocytosis/phagocytosis but also in cell adhesion and migration PMID: 17947679
    5. DCL1 equilibrium unfolding is characterized at the amino acid level. PMID: 19317456

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  • 亚细胞定位：
    Membrane; Single-pass type I membrane protein. Cell projection, filopodium. Cytoplasm, cell cortex. Cell projection, microvillus. Note=Colocalizes with F-actin in filopodia, cellular cortex and microvilli of the apical cell surface.
  • 组织特异性：
    Expressed at moderate levels in monocytes, myeloid blood dendritic cells and granulocytes and at low levels in plasmacytoid blood dendritic cells, monocyte-derived ma crophages and monocyte-derived dendritic cells, with no expression detected in T-lymphoc
  • 数据库链接：

    HGNC: 30843

    OMIM: 612246

    KEGG: hsa:9936

    STRING: 9606.ENSP00000259053

    UniGene: Hs.130014