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CDC42EP3 Antibody

  • 货号：
    CSB-PA006654
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of K562 cells using Cdc42EP3 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q9UKI2
  • 基因名：
    CDC42EP3
  • 别名：
    CDC42EP3 antibody; BORG2 antibody; CEP3Cdc42 effector protein 3 antibody; Binder of Rho GTPases 2 antibody; MSE55-related Cdc42-binding protein antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the N-terminal region of Human Cdc42EP3.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:40000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts.
  • 基因功能参考文献：
    1. Results provide evidence that Cdc42EP3 function in cancer-associated fibroblasts relies on tight regulation by Cdc42. PMID: 27248291
    2. The expression of CDC42EP3 mRNA was significantly increased by 19.7% in dorsal prefrontal cortex in patient with schizophrenia. PMID: 20385374
  • 亚细胞定位：
    Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton.
  • 蛋白家族：
    BORG/CEP family
  • 组织特异性：
    Highly expressed in the heart and weakly in the brain.
  • 数据库链接：

    HGNC: 16943

    OMIM: 606133

    KEGG: hsa:10602

    STRING: 9606.ENSP00000295324

    UniGene: Hs.369574