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CDX4 Antibody

  • 货号：
    CSB-PA005129LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: RAW264.7 whole cell lysate, Hela whole cell lysate, HepG2 whole cell lysate, Mouse liver tissue
      All lanes: CDX4 antibody at 3μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 31 kDa
      Observed band size: 37 kDa
    • Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA005129LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA005129LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) CDX4 Polyclonal antibody
  • Uniprot No.：
    O14627
  • 基因名：
    CDX4
  • 别名：
    Caudal-type homeobox protein 4 antibody; CDX4 antibody; CDX4_HUMAN antibody; Homeobox protein CDX-4 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Homeobox protein CDX-4 protein (16-174AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，CDX4 Antibody (CSB-PA005129LA01HU)，的标记方式是Non-conjugated。对于CDX4 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA005129LB01HU CDX4 Antibody, HRP conjugated ELISA
    FITC CSB-PA005129LC01HU CDX4 Antibody, FITC conjugated
    Biotin CSB-PA005129LD01HU CDX4 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 基因功能参考文献：
    1. Gene expression analyses on WNT-dependent KDR(+)CD235a(-) definitive hematopoietic mesoderm and WNT-independent KDR(+)CD235a(+) primitive hematopoietic mesoderm revealed strong CDX gene expression within definitive hematopoietic mesoderm. Temporal expression analyses revealed that CDX4 was expressed exclusively within definitive hematopoietic KDR(+)CD235a(-) mesoderm in a WNT- and fibroblast growth factor-dependent manner PMID: 28408465
    2. CDX4 gene was introduced to reprogram adipose tissue derived mesenchymal stem cells to differentiate along the hematopoietic lineage. PMID: 22721648
    3. a molecular mechanisms through which increased expression of HoxA10 increases Cdx4 expression by direct CDX4 activation and by Fgf2-induced beta-catenin activity. This results in Cdx4-induced HoxA10-expression, creating a positive feedback mechanism PMID: 23038246
    4. positive feedback relationship between HoxA10 and Cdx4, which potentially amplified the contribution of either transcription factor to the pathogenesis of AML. PMID: 21471217
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Caudal homeobox family
  • 数据库链接：

    HGNC: 1808

    OMIM: 300025

    KEGG: hsa:1046

    STRING: 9606.ENSP00000362613

    UniGene: Hs.553488