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CEP83 Antibody

  • 货号：
    CSB-PA896730ESR1HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: CEP83 antibody at 2.41 μg/ml + Raji whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 83, 68 kDa
      Observed band size: 83, 55 kDa
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA896730ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA896730ESR1HU at dilution of 1:100
    • Immunofluorescent analysis of PC-3 cells using CSB-PA896730ESR1HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) CEP83 Polyclonal antibody
  • Uniprot No.：
    Q9Y592
  • 基因名：
    CEP83
  • 别名：
    CEP83 antibody; CCDC41Centrosomal protein of 83 kDa antibody; Cep83 antibody; Coiled-coil domain-containing protein 41 antibody; Renal carcinoma antigen NY-REN-58 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Centrosomal protein of 83 kDa protein (34-260AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Component of the distal appendage region of the centriole involved in the initiation of primary cilium assembly. May collaborate with IFT20 in the trafficking of ciliary membrane proteins from the Golgi complex to the cilium during the initiation of primary cilium assembly.
  • 基因功能参考文献：
    1. We have identified mutations in CEP83, another distal appendages component encoding gene, as a cause of infantile nephronophthisis associated with central nervous system abnormalities in half of the individuals. PMID: 24882706
    2. CCDC41 is required for the docking of ciliary vesicles PMID: 23530209
  • 相关疾病：
    Nephronophthisis 18 (NPHP18)
  • 亚细胞定位：
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localizes specifically to the distal appendage region of the centriole, which anchors the mother centriole to the plasma membrane. Localizes to centrioles at all stages of the cell cycle, including mitosis.
  • 蛋白家族：
    CEP83 family
  • 数据库链接：

    HGNC: 17966

    OMIM: 615847

    KEGG: hsa:51134

    STRING: 9606.ENSP00000344655

    UniGene: Hs.279209