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CKMT2 Antibody

  • 货号：
    CSB-PA698913
  • 规格：
    ￥1100
  • 图片：
    • The image is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA698913(CKMT2 Antibody) at dilution 1/60. (Original magnification: ×200)
    • The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA698913(CKMT2 Antibody) at dilution 1/60. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse heart tissue, Primary antibody: CSB-PA698913(CKMT2 Antibody) at dilution 1/700, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
  • 其他：

产品详情

  • Uniprot No.：
    P17540
  • 基因名：
    CKMT2
  • 别名：
    CKMT 2 antibody; Basic-type mitochondrial creatine kinase antibody; CKMT2 antibody; CPK antibody; Creatine kinase mitochondrial 2 antibody; Creatine kinase mitochondrial 2 (sarcomeric) antibody; Creatine kinase S-type antibody; creatine kinase S-type, mitochondrial antibody; Creatine kinase, sarcomeric mitochondrial antibody; KCRS_HUMAN antibody; Mib CK antibody; Mib-CK antibody; mitochondrial antibody; OTTHUMP00000147542 antibody; S-MtCK antibody; Sarcomeric mitochondrial creatine kinase antibody; SMTCK antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human CKMT2
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
  • 基因功能参考文献：
    1. three C-terminal lysines determine high affinity sMtCK/cardiolipin interaction and its effects on MtCK structure, whereas low level binding and some effect on membrane fluidity depend on other structural components PMID: 15044463
    2. After the training period, intracellular energetic units had a higher control of mitochondrial respiration by creatine linked to a more efficient functional coupling adenine nucleotide translocase-mitochondrial creatine kinase. PMID: 16020522
    3. CK2alpha has a role in progression of acute myeloid leukemia PMID: 17289898
  • 亚细胞定位：
    Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
  • 蛋白家族：
    ATP:guanido phosphotransferase family
  • 组织特异性：
    Sarcomere-specific. Found only in heart and skeletal muscles.
  • 数据库链接：

    HGNC: 1996

    OMIM: 123295

    KEGG: hsa:1160

    STRING: 9606.ENSP00000254035

    UniGene: Hs.80691