Your Good Partner in Biology Research

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. CLDN17 Antibody

CLDN17 Antibody

  • 货号：
    CSB-PA004868
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of Raji BT474 K562 mouse heart mouse skeletal muscle cells using Claudin-17 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    P56750
  • 基因名：
    CLDN17
  • 别名：
    CLDN17; UNQ758/PRO1489; Claudin-17
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human Claudin-17.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Channel-forming tight junction protein with selectivity for anions, including chloride and bicarbonate, and for solutes smaller than 9 Angstrom in diameter. In the kidney proximal tubule, may be involved in quantitative reabsorption of filtered anions. Does not affect water permeability.
  • 基因功能参考文献：
    1. The structural features of Cldn17 contributing to anion channel formation are presented in this work. PMID: 26194246
    2. Claudin 17 expression was down-regulated in gastric cancer. PMID: 24325792
    3. CLDN17, clustered with CLDN8 at human chromosome 21q22.11, is a four-transmembrane protein with WWCC motif, defined by W-X(17-22)-W-X(2)-C-X(8-10)-C. PMID: 12736707
  • 亚细胞定位：
    Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Claudin family
  • 组织特异性：
    In the kidney, expressed in the proximal tubule and in the Henle's loop. In the distal convoluted tubule, not expressed in all tubules. Not detected in the collecting duct (at protein level).
  • 数据库链接：

    HGNC: 2038

    OMIM: 617005

    KEGG: hsa:26285

    STRING: 9606.ENSP00000286808

    UniGene: Hs.258589