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CLSTN2 Antibody

  • 货号：
    CSB-PA863978LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA863978LA01HU at dilution of 1:100
    • Immunofluorescent analysis of HepG2 cells using CSB-PA863978LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) CLSTN2 Polyclonal antibody
  • Uniprot No.：
    Q9H4D0
  • 基因名：
    CLSTN2
  • 别名：
    CLSTN2 antibody; CS2Calsyntenin-2 antibody; Alcadein-gamma antibody; Alc-gamma antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Calsyntenin-2 protein (473-673AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，CLSTN2 Antibody (CSB-PA863978LA01HU)，的标记方式是Non-conjugated。对于CLSTN2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA863978LB01HU CLSTN2 Antibody, HRP conjugated ELISA
    FITC CSB-PA863978LC01HU CLSTN2 Antibody, FITC conjugated
    Biotin CSB-PA863978LD01HU CLSTN2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May modulate calcium-mediated postsynaptic signals.
  • 基因功能参考文献：
    1. Study did not find support for an association of KIBRA either alone or in combination with CLSTN2 with memory performance or hippocampal volume, nor did variation in these genes influence longitudinal memory decline or hippocampal atrophy in older adults PMID: 26415670
    2. The results of this study supports the view that effects of KIBRA and CLSTN2 polymorphisms genetic polymorphisms on cognitive functioning may be most easily disclosed at suboptimal levels of cognitive ability, such as in old-age depression. PMID: 25080189
    3. No increased risk of any type of late development, and cognitive impairment was associated with CLSTN2 (rs6439886) PMID: 21643791
    4. This study showed that the KIBRA and CLSTN2 genes interactively modulate episodic memory performance. PMID: 19804789
    5. Alcadein and amyloid beta-protein precursor regulates FE65-dependent gene transactivation [alcalpha1, alcbeta, alcgamma] PMID: 15037614
    6. calsyntenins play an essential role in learning and this role is modulated both by CLSTN2 genotype and, during adolescent development, by exposure to tobacco smoke. PMID: 19058786

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  • 亚细胞定位：
    Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane. Golgi apparatus membrane. Cell junction, synapse, postsynapse. Cell projection, dendrite.
  • 组织特异性：
    Restricted to the brain.
  • 数据库链接：

    HGNC: 17448

    OMIM: 611323

    KEGG: hsa:64084

    STRING: 9606.ENSP00000402460

    UniGene: Hs.158529