CNIH3 Antibody
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货号:CSB-PA005650GA01HU
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规格:¥3,900
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其他:
产品详情
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Uniprot No.:Q8TBE1
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基因名:CNIH3
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别名:CNIH3; Protein cornichon homolog 3; CNIH-3; Cornichon family AMPA receptor auxiliary protein 3
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宿主:Rabbit
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反应种属:Human,Mouse,Rat
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免疫原:Human CNIH3
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免疫原种属:Homo sapiens (Human)
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抗体亚型:IgG
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纯化方式:Antigen Affinity Purified
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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产品提供形式:Liquid
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应用范围:ELISA,WB
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Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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靶点详情
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功能:Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization.
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基因功能参考文献:
- Study's convergent findings in humans and mice support CNIH3 involvement in the pathophysiology of opioid dependence, complementing prior studies implicating the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) glutamate system PMID: 26239289
- Significant upregulation of CNIH-3 mRNA expression was found in schizophrenia. PMID: 23103966
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亚细胞定位:Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
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蛋白家族:Cornichon family
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组织特异性:Expression is up-regulated in dorsolateral prefrontal cortex of patients with schizophrenia (postmortem brain study).
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数据库链接:
HGNC: 26802
KEGG: hsa:149111
STRING: 9606.ENSP00000272133
UniGene: Hs.731723
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