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COG4 Antibody

  • 货号：
    CSB-PA881003ESR2HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: COG4 antibody at 4.85µg/ml
      Lane 1: Mouse liver tissue
      Lane 2: Mouse gonadal tissue
      Lane 3: K562 whole cell lysate
      Lane 4: Hela whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 90, 39, 82 kDa
      Observed band size: 90 kDa
    • Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA881003ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA881003ESR2HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) COG4 Polyclonal antibody
  • Uniprot No.：
    Q9H9E3
  • 基因名：
    COG4
  • 别名：
    COG4Conserved oligomeric Golgi complex subunit 4 antibody; COG complex subunit 4 antibody; Component of oligomeric Golgi complex 4 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Conserved oligomeric Golgi complex subunit 4 protein (506-785AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1.
  • 基因功能参考文献：
    1. A novel R729W missense mutation in COG4 was associated with the congenital disorder of glycosylation type II. PMID: 19494034
    2. The 1.9 A crystal structure of a Cog4 C-terminal fragment, was determined. Arg 729 is found to occupy a key position at the center of a salt bridge network, thereby stabilizing Cog4's small C-terminal domain. PMID: 19651599
  • 相关疾病：
    Congenital disorder of glycosylation 2J (CDG2J)
  • 亚细胞定位：
    Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族：
    COG4 family
  • 数据库链接：

    HGNC: 18620

    OMIM: 606976

    KEGG: hsa:25839

    STRING: 9606.ENSP00000315775

    UniGene: Hs.208680