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COPS7B Antibody

  • 货号：
    CSB-PA872526LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: Mouse brain tissue, Mouse stomach tissue
      All lanes: COPS7B antibody at 3µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 30, 19, 31 kDa
      Observed band size: 30 kDa
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA872526LA01HU at dilution of 1:100
    • Immunofluorescent analysis of Hela cells using CSB-PA872526LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) COPS7B Polyclonal antibody
  • Uniprot No.：
    Q9H9Q2
  • 基因名：
    COPS7B
  • 别名：
    COP9 Complex Homolog Subunit 7b antibody; COP9 Constitutive Photomorphogenic Homolog Subunit 7b antibody; COP9 Signalasome Subunit 7b antibody; COP9 signalosome complex subunit 7b antibody; COPS7B antibody; CSN7B_HUMAN antibody; JAB1 Containing Signalosome Subunit 7b antibody; JAB1-containing signalosome subunit 7b antibody; SGN7b antibody; Signalosome subunit 7b antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human COP9 signalosome complex subunit 7b protein (1-157AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，COPS7B Antibody (CSB-PA872526LA01HU)，的标记方式是Non-conjugated。对于COPS7B Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA872526LB01HU COPS7B Antibody, HRP conjugated ELISA
    FITC CSB-PA872526LC01HU COPS7B Antibody, FITC conjugated
    Biotin CSB-PA872526LD01HU COPS7B Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:2000-1:5000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    CSN7/EIF3M family, CSN7 subfamily
  • 数据库链接：

    HGNC: 16760

    OMIM: 616010

    KEGG: hsa:64708

    STRING: 9606.ENSP00000272995

    UniGene: Hs.335061