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COX16 Antibody

  • 货号：
    CSB-PA241484
  • 规格：
    ￥1100
  • 图片：
    • The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA241484(COX16 Antibody) at dilution 1/50. (Original magnification: ×200)
    • The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using CSB-PA241484(COX16 Antibody) at dilution 1/50. (Original magnification: ×200)
  • 其他：

产品详情

  • Uniprot No.：
    Q9P0S2
  • 基因名：
    COX16
  • 别名：
    C14orf112 antibody; COX16 antibody; COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) antibody; COX16_HUMAN antibody; Cytochrome c oxidase assembly factor antibody; Cytochrome c oxidase assembly protein COX16 homolog antibody; HSPC203 antibody; mitochondrial antibody; PTD019 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human COX16
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:500-1:2000
    IHC 1:25-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Promotes the insertion of copper into the active site of cytochrome c oxidase subunit II (MT-CO2/COX2). Interacts specifically with newly synthesized MT-CO2/COX and its copper center-forming metallochaperones SCO1, SCO2 and COA6. Probably facilitates MT-CO2/COX2 association with the MITRAC assembly intermediate containing MT-CO1/COX1, thereby participating in merging the MT-CO1/COX1 and MT-CO2/COX2 assembly lines.
  • 基因功能参考文献：
    1. COX16 is required for assembly of cytochrome C oxidase in human cells and is involved in copper delivery to COX2. PMID: 29355485
  • 亚细胞定位：
    Mitochondrion inner membrane; Single-pass membrane protein.
  • 蛋白家族：
    COX16 family
  • 组织特异性：
    Widely expressed. Expressed at higher level in skeletal muscle, heart and liver.
  • 数据库链接：

    HGNC: 20213

    KEGG: hsa:51241

    STRING: 9606.ENSP00000374562

    UniGene: Hs.709581