CRISP3 Antibody

1. results suggest that overexpression of CRISP-3 in prostate tumor may maintain higher PSA expression and lower ANXA1 expression PMID: 26369530
2. These data suggest roles for epithelial and neutrophil-derived CRISP3 in postmenstrual endometrial repair and regeneration PMID: 25715794
3. up-regulation of the mRNA encoding cysteine-rich secretory protein 3 (CRISP3), a glycoprotein with unknown function that is secreted from multiple exocrine glands, was correlated with HCV resistance. PMID: 24978310
4. Strong CRISP3 expression is associated with unfavorable tumor phenotype and early recurrence in prostate cancers PMID: 23196798
5. terminal beta-strands of PSP94 contact the first alpha-helix and the hinge region of CRISP-3 PMID: 23375721
6. MSMB and CRISP3 were widely distributed in ovaries and in ovarian tumors; the expression of MSMB fits well with a tumor-suppressor function in ovarian carcinogenesis. PMID: 22993349
7. up-regulation of CRISP3 is associated with prostate carcinomas with the TMPRSS2-ERG fusion gene. PMID: 21814574
8. We found no correlation between CRISP3 expression and biochemical recurrence. PMID: 21240253
9. Expression levels of AR and CRISP3 were not affected by short-term ADT but were high in castration-resistant prostate cancer (CRPC) and metastases. PMID: 20680031
10. Either PSP94 or CRISP-3 alone can induce growth inhibition in prostate cancer cells in a cell line specific manner. PMID: 20676114
11. Additional transcription changes likely associated with Th2-like eosinophilic inflammation were prominent and included decreased CRISP2&3. PMID: 20625511
12. Complex binding of CRISP proteins by A1BG and other proteins may interfere with the detection and function of these proteins. PMID: 20116414
13. The presence of CRISP-3 in peroxidase-negative granules of neutrophils, in granules of eosinophils, and in exocrine secretions indicates a role in the innate host defense. PMID: 12223513
14. in situ hybridization experiments indicated that CRISP-3 mRNA is epithelial-specific and is up-regulated in prostate adenocarcinoma compared with benign prostate tissue; a potential biomarker for prostate cancer PMID: 12433721
15. high levels of CRISP-3 in acinar cells dedifferentiating into small proliferating ductal cells in chronic pancreatitis suggests a role of this molecule in the pathophysiology of chronic pancreatitis PMID: 12647793
16. alpha-1-B glycoprotein-CRISP-3 complex displays a similar function in protecting the circulation from a potentially harmful effect of free CRISP-3 PMID: 15461460
17. Human CRISP-3 is a quantitatively minor seminal plasma protein not associated with prostasomes. CRISP-3 was found in secretory epithelium throughout the male genital tract, with particularly high expression in cauda epididymis and ampulla vas deferens. PMID: 15867000
18. Structural similarity with an MSP-binding protein from blood plasma suggests that CRISP-3 binds MSP through its aminoterminal SCP-domain. PMID: 15950934
19. Strong immunostaining for CRISP-3 is common in high-grade prostatic-intraepithelial-neoplasia and preserved in prostatic csncer. PMID: 16388501
20. Predictor of recurrence after radical prostatectomy for localized prostate cancer. PMID: 17634540
21. CRISP-3 pathology occurred in acini remote from lymphocyte foci and may represent some systemic effect in Sjogren Syndrome. PMID: 17665393
22. A tentative structure for the hMSP-CRISP-3 complex using the known crystal structure of triflin as a model of CRISP-3 was presented. PMID: 19026612
23. Results suggest that absence of a local reduction in expression of CRISP-3 in decidualized endometrium of women with EP may be due to reduced exposure to hCG due to the ectopic location of the trophoblast. PMID: 19282327

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HGNC: 16904

KEGG: hsa:10321

STRING: 9606.ENSP00000389026

UniGene: Hs.404466