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Capsid protein VP1 Antibody

  • 货号：
    CSB-PA362102LA01HPM
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Human parvovirus B19 N/A Polyclonal antibody
  • Uniprot No.：
    P07299
  • 基因名：
    N/A
  • 别名：
    Minor capsid protein VP1 antibody; EC 3.1.1.4 antibody; Coat protein VP1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human parvovirus B19
  • 免疫原：
    Recombinant Human parvovirus B19 Capsid protein VP1 protein (228-781AA)
  • 免疫原种属：
    Human parvovirus B19
  • 标记方式：
    Non-conjugated

    本页面中的产品，Capsid protein VP1 Antibody (CSB-PA362102LA01HPM)，的标记方式是Non-conjugated。对于Capsid protein VP1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA362102LB01HPM Capsid protein VP1 Antibody, HRP conjugated ELISA
    FITC CSB-PA362102LC01HPM Capsid protein VP1 Antibody, FITC conjugated
    Biotin CSB-PA362102LD01HPM Capsid protein VP1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Capsid protein self-assembles to form an icosahedral capsid with a T=1 symmetry, about 20 nm in diameter, and consisting of 60 copies of two size variants of the capsid proteins, VP1 and VP2, which differ by the presence of an N-terminal extension in the minor protein VP1. The capsid encapsulates the genomic ssDNA. Binds to erythroid progenitor cells expressing high levels of P antigen and uses host ITGA5-ITGB1 and XRCC5/Ku80 autoantigen as coreceptors on the cell surface to provide virion attachment to target cell. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. Binding to the host receptors also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, specifically its phospholipase A2-like region. The additional N-terminal region of isoform Minor capsid protein VP1, called VP1u, may serve as a lipolytic enzyme to breach the endosomal membrane during entry into host cell and might contribute to virus transport to the nucleus.
  • 亚细胞定位：
    [Isoform Minor capsid protein VP1]: Virion. Host nucleus. Host cytoplasm.; [Isoform Major capsid protein VP2]: Virion. Host nucleus. Host cytoplasm.
  • 蛋白家族：
    Parvoviridae capsid protein family