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Ccl9 Antibody

  • 货号：
    CSB-PA09119A0Rb
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Mus musculus (Mouse) Ccl9 Polyclonal antibody
  • Uniprot No.：
    P51670
  • 基因名：
    Ccl9
  • 别名：
    CCF18 antibody; Ccl9 antibody; CCL9(31-101) antibody; CCL9_MOUSE antibody; Chemokine CC motif ligand 9 antibody; Macrophage inflammatory protein 1-gamma antibody; Macrophage inflammatory protein-related protein 2 antibody; MIP-1-gamma antibody; MRP-2 antibody; SCYA10 antibody; SCYA9 antibody; Small inducible cytokine A9 antibody; Small-inducible cytokine A9 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Mouse
  • 免疫原：
    Recombinant Mouse C-C motif chemokine 9 protein (22-114AA)
  • 免疫原种属：
    Mus musculus (Mouse)
  • 标记方式：
    Non-conjugated

    本页面中的产品，Ccl9 Antibody (CSB-PA09119A0Rb)，的标记方式是Non-conjugated。对于Ccl9 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA09119B0Rb Ccl9 Antibody, HRP conjugated ELISA
    FITC CSB-PA09119C0Rb Ccl9 Antibody, FITC conjugated
    Biotin CSB-PA09119D0Rb Ccl9 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.1mol/L NaCl, 15mmol/L NaN3, PH7.2
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Monokine with inflammatory, pyrogenic and chemokinetic properties. Circulates at high concentrations in the blood of healthy animals. Binding to a high-affinity receptor activates calcium release in neutrophils. It also inhibits colony formation of bone marrow myeloid immature progenitors.
  • 基因功能参考文献：
    1. CCL9 secreted by splenic macrophages induces a CCR1dependent accumulation of MDSCs. PMID: 30365155
    2. Results show that MIP-1g promotes tumor cell growth in vitro through the activation of NFkB pathway in colorectal tumor cells. PMID: 28108624
    3. we report that chemokine CCL9 was highly induced in Gr-1(+)CD11b(+) immature myeloid cells and in premetastatic lung in tumor-bearing mice PMID: 26483204
    4. Plasmid codelivery of murine CCL19 and CCL28 enhanced Ag-specific systemic and mucosal Ab responses to HIV-1 gp140, augmented balanced Th1/Th2 responses, and increased lymphocyte subsets in various lymphoid tissues. PMID: 23858028
    5. There is protein-DNA interaction between ETV5 and Ccl9, suggesting that ETV5 might be a direct regulator of Ccl9 expression. PMID: 20799334
    6. Results reveal the potential involvement of CCL9 and CCR1 in macrophage and microglial cells by CpG-ODNs and may help understanding the role of the chemokine/chemokine receptor pairs in macrophage/microglia under physiologic and pathologic conditions. PMID: 19883904
    7. MRP-2 may be an important contributing factor in the development of atherosclerosis PMID: 12173416
    8. CCL9 and its receptor CCR1 are the major chemokine and receptor species expressed by osteoclasts, CCL9 has a role in the regulation of bone resorption PMID: 12397598
    9. An important role for CCL9 is demonstrated in the recruitment of CD11b+ dendritic cells to the dome regions of mouse Peyer's patches. PMID: 12960300
    10. MIP-1 gamma plays an important role in the differentiation & survival of osteoclasts, & bone resorption, most likely via an autocrine pathway. PMID: 15265944
    11. Keratinocyte-derived chemokine (KC) and MIP-2 alpha differ in their mediation of neutrophil function (apoptosis and chemotaxis) and contribution to the pathogenesis of lung injury following hemorrhage subsequent to sepsis. PMID: 15961314
    12. BCR/ABL repressed CCL9 expression at the transcriptional level PMID: 17160016
    13. involved in calcium mobilization and chemotaxis PMID: 11500837

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Intercrine beta (chemokine CC) family
  • 组织特异性：
    Expressed mainly in the liver, lung, and the thymus, although some expression has been detected in a wide variety of tissues except brain.
  • 数据库链接：

    KEGG: mmu:20308

    STRING: 10090.ENSMUSP00000019266

    UniGene: Mm.416125