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DAP3 Antibody

  • 货号：
    CSB-PA922061
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA922061(DAP3 Antibody) at dilution 1/15, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 12%SDS-PAGE, Lysate: 30 μg, Lane: Human lymphoma tissue, Primary antibody: CSB-PA922061(DAP3 Antibody) at dilution 1/150, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
  • 其他：

产品详情

  • Uniprot No.：
    P51398
  • 基因名：
    DAP3
  • 别名：
    28S ribosomal protein S29 antibody; 28S ribosomal protein S29 mitochondrial antibody; bMRP10 antibody; DAP 3 antibody; DAP-3 antibody; Dap3 antibody; Death associated protein 3 antibody; Death-associated protein 3 antibody; DKFZp686G12159 antibody; FLJ12817 antibody; Ionizing radiation resistance conferring protein antibody; MGC126058 antibody; MGC126059 antibody; Mitochondrial 28S ribosomal protein S29 antibody; mitochondrial antibody; MITOCHONDRIAL RIBOSOMAL PROTEIN S29 antibody; MRP S29 antibody; MRP-S29 antibody; MRPS29 antibody; OTTHUMP00000033480 antibody; OTTHUMP00000033481 antibody; PSD-95/SAP90-binding protein 3 antibody; RT29_HUMAN antibody; S29mt antibody; SAP90/PSD-95-associated protein 3 antibody; SAPAP3 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human DAP3
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:5000
    WB 1:200-1:1000
    IHC 1:10-1:50
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in mediating interferon-gamma-induced cell death.
  • 基因功能参考文献：
    1. DAP3 plays important roles in mitochondrial function and dynamics PMID: 26306039
    2. DAP3 silencing contributes to breast carcinogenesis. PMID: 25738636
    3. Knockdown of DAP3 expression promoted cell migration. PMID: 24300973
    4. Study demonstrates an inverse association between DAP3 mRNA levels and tumour stage and clinical outcome in breast cancer. PMID: 22287761
    5. identified a novel DAP3-binding protein termed death ligand signal enhancer (DELE); results demonstrated the biological significance of DELE for apoptosis signal mediated by death receptors PMID: 20563667
    6. show that interferon-beta promoter stimulator 1 (IPS-1) binds DAP3 and induces anoikis by caspase activation. PMID: 19644511
    7. Functional interaction between the pro-apoptotic DAP3 and the glucocorticoid receptor PMID: 12099703
    8. not involved in TRAIL-induced apoptosis PMID: 12359235
    9. DAP3 has a role in the molecular pathway that culminates in fragmented mitochondria PMID: 15175341
    10. DAP3 gene might be associated with the mechanisms responsible for adult bronchial asthma and contribute to airway inflammation and remodeling PMID: 15179560
    11. DAP3 has a role in anoikis signaling and in apoptosis induction caused by cell detachment PMID: 15302871
    12. High DAP3 expression is correlated with thymoma stage PMID: 15679048
    13. study investigated the phosphorylation status of ribosomal DAP3 and mapped the phosphorylation sites by tandem mass spectrometry PMID: 18227431
    14. Complex I and DAP3, hNOA1 may play a role in mitochondrial respiration and apoptosis. PMID: 19103604
    15. DAP3 may participate in mitochondrial maintenance and play a role in the balance between mitochondrial homoeostasis and tumourigenesis in thyroid oncocytic tumors. PMID: 19536094

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  • 亚细胞定位：
    Mitochondrion.
  • 蛋白家族：
    Mitochondrion-specific ribosomal protein mS29 family
  • 组织特异性：
    Ubiquitous.
  • 数据库链接：

    HGNC: 2673

    OMIM: 602074

    KEGG: hsa:7818

    STRING: 9606.ENSP00000341692

    UniGene: Hs.516746