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DCN Antibody

  • 货号：
    CSB-PA006554LA01BO
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: DCN antibody at 6µg/ml + Jurkat whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 40 kDa
      Observed band size: 40 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Bovine DCN Polyclonal antibody
  • Uniprot No.：
    P21793
  • 基因名：
  • 别名：
    DCN antibody; Decorin antibody; Bone proteoglycan II antibody; PG-S2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Bovine, Human
  • 免疫原：
    Recombinant Bovine Decorin protein (31-360AA)
  • 免疫原种属：
    Bovine
  • 标记方式：
    Non-conjugated

    本页面中的产品，DCN Antibody (CSB-PA006554LA01BO)，的标记方式是Non-conjugated。对于DCN Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA006554LB01BO DCN Antibody, HRP conjugated ELISA
    FITC CSB-PA006554LC01BO DCN Antibody, FITC conjugated
    Biotin CSB-PA006554LD01BO DCN Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May affect the rate of fibrils formation.
  • 基因功能参考文献：
    1. downregulation associated with proliferation, remodeling and vascularization of placental tissues PMID: 25012297
    2. The inclusion of decorin proteoglycan during fibrillogenesis of type I collagen increases the modulus and tensile strength of resulting collagen gels. PMID: 23608680
    3. These findings reveal a novel role of DCN as an antagonistic ligand for VEGFR-2. PMID: 21659473
    4. Data show that biglycan, collagen type I, collagen type II, decorin, and versican were significantly affected by vibration duration, frequency, and amplitude. PMID: 20386503
    5. Results suggest that decorin contributes to the formation and stabilization of collagen fibres in the perimysium that support muscle fibres assembled with myogenesis. PMID: 12097842
    6. decorin is a dimer in solution PMID: 12601001
    7. decorin-induced fibroblast cytoskeletal and signalling changes result in an increased cell migration; potential role in the remodelling process PMID: 14600270
    8. Transduced bovine decorin synthesized de novo by rat arterial smooth muscle cells increases type I collagen synthesis and enhances contraction of collagen gels. PMID: 14615389
    9. The results indicate that CTGF suppresses the synthesis of biglycan but newly induced that of decorin in the cells when the cell density is low. PMID: 15313168
    10. crystal structure of the dimeric protein core PMID: 15501918
    11. a novel collagen binding domain in decorin acts cooperatively with leucine-rich repeat 4 to mask the alpha2beta1 integrin-binding site on collagen, an important sequence for the phagocytosis of collagen fibrils PMID: 15811857
    12. The rupture force of single bonds between decorins (GAG chains interaction) was determined directly as 16.5+/-5.1 pN using a laser tweezers/interferometer single molecular nanomechanical testing system. PMID: 16263082
    13. analysis of decorin from different bovine tissues PMID: 16293388

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  • 亚细胞定位：
    Secreted, extracellular space, extracellular matrix.
  • 蛋白家族：
    Small leucine-rich proteoglycan (SLRP) family, SLRP class I subfamily
  • 数据库链接：

    KEGG: bta:280760

    STRING: 9913.ENSBTAP00000004562

    UniGene: Bt.23178