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DCTN3 Antibody

  • 货号：
    CSB-PA006566ESR1HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA006566ESR1HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) DCTN3 Polyclonal antibody
  • Uniprot No.：
    O75935
  • 基因名：
    DCTN3
  • 别名：
    DCNT22 antibody; DCTN 22 antibody; DCTN22 antibody; Dctn3 antibody; DCTN3_HUMAN antibody; dynactin 3 (p22) antibody; dynactin 3 antibody; dynactin 3 isoform 1 antibody; Dynactin complex subunit 22 kDa subunit antibody; dynactin light chain antibody; Dynactin subunit 3 antibody; p22 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Dynactin subunit 3 protein (1-176AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Together with dynein may be involved in spindle assembly and cytokinesis.
  • 基因功能参考文献：
    1. Study found that in peripheral blood mononuclear cells the median expression of KIFC3, KIF1B, and KIF5C was much lower than the expression of dynactin subunits DCTN1 and DCTN3, in both sporadic amyotrophic lateral sclerosis and healthy cases PMID: 26954557
  • 亚细胞定位：
    Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Cleavage furrow. Midbody. Note=Localizes to punctate cytoplasmic structures and to the centrosome during interphase, and to kinetochores and to spindle poles throughout mitosis. Colocalizes with dynein to the cleavage furrow and to midbody of dividing cells.
  • 蛋白家族：
    Dynactin subunit 3 family
  • 组织特异性：
    Ubiquitously expressed. Highly expressed in muscle and pancreas and detected at lower levels in brain.
  • 数据库链接：

    HGNC: 2713

    OMIM: 607387

    KEGG: hsa:11258

    STRING: 9606.ENSP00000259632

    UniGene: Hs.511768