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DDX18 Antibody

  • 货号：
    CSB-PA882116LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunofluorescence staining of Hela cells with CSB-PA882116LA01HU at 1:333, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) DDX18 Polyclonal antibody
  • Uniprot No.：
    Q9NVP1
  • 基因名：
    DDX18
  • 别名：
    ATP dependent RNA helicase DDX18 antibody; ATP-dependent RNA helicase DDX18 antibody; DDX 18 antibody; DDX18 antibody; DDX18_HUMAN antibody; DEAD (Asp Glu Ala Asp) box polypeptide 18 antibody; DEAD box polypeptide 18 antibody; DEAD box protein 18 antibody; FLJ33908 antibody; MrDb antibody; Myc regulated DEAD box protein antibody; Myc-regulated DEAD box protein antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human ATP-dependent RNA helicase DDX18 protein (32-110AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，DDX18 Antibody (CSB-PA882116LA01HU)，的标记方式是Non-conjugated。对于DDX18 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA882116LB01HU DDX18 Antibody, HRP conjugated ELISA
    FITC CSB-PA882116LC01HU DDX18 Antibody, FITC conjugated
    Biotin CSB-PA882116LD01HU DDX18 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IF 1:200-1:500
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Probable RNA-dependent helicase.
  • 基因功能参考文献：
    1. Data show that odulation of RNA helicase DDX18 directly affects growth of tamoxifen-resistant cells, suggesting that it may be a critical downstream effector of the estrogen receptors (ERs) and high mobility group box 2 (HMGB2) complex. PMID: 25284587
    2. We identified 4 nonsynonymous sequence variants of DDX18 in acute myeloid leukemia patient samples PMID: 21653321
    3. findings suggest that MrDb is important for cell proliferation and that its inhibition could prevent tumor cell proliferation. PMID: 18351129
  • 亚细胞定位：
    Nucleus, nucleolus. Chromosome.
  • 蛋白家族：
    DEAD box helicase family, DDX18/HAS1 subfamily
  • 数据库链接：

    HGNC: 2741

    OMIM: 606355

    KEGG: hsa:8886

    STRING: 9606.ENSP00000263239

    UniGene: Hs.744922