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DHRS9 Antibody

  • 货号：
    CSB-PA006867GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9BPW9
  • 基因名：
    DHRS9
  • 别名：
    3 alpha hydroxysteroid dehydrogenase antibody; 3-@alpha-HSD antibody; 3-@alpha-hydroxysteroid dehydrogenase antibody; 3-alpha hydroxysteroid dehydrogenase antibody; 3-alpha-HSD antibody; 3alpha HSD antibody; Dehydrogenase/reductase SDR family member 9 antibody; DHRS9 antibody; DHRS9_HUMAN antibody; NADP dependent retinol dehydrogenase/reductase antibody; NADP-dependent retinol dehydrogenase/reductase antibody; RDH-E2 antibody; Rdh15 antibody; RDHE2 antibody; RDHL antibody; RDHTBE antibody; retinol dehydrogenase homolog antibody; Retinol dehydrogenase; tracheobronchiol epithelail cell-specific antibody; RETSDR8 antibody; SDR family; member 9 antibody; SDR9C4 antibody; short chain dehydrogenase/reductase family 9 antibody; short chain dehydrogenase/reductase family 9C; member 4 antibody; Short chain dehydrogenase/reductase retSDR8 antibody; Short-chain dehydrogenase/reductase retSDR8 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human DHRS9
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    3-alpha-hydroxysteroid dehydrogenase that converts 3-alpha-tetrahydroprogesterone (allopregnanolone) to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone. Plays also a role in the biosynthesis of retinoic acid from retinaldehyde. Can utilize both NADH and NADPH.
  • 基因功能参考文献：
    1. The study findings suggest that DHRS9 might be a useful diagnostic and prognostic marker for oral squamous cell carcinoma PMID: 30149992
    2. DHRS9 is a specific and stable marker of human regulatory macrophages. PMID: 28594751
    3. decreased expression of DHRS9 correlates with tumor progression and may serve as a potential prognostic biomarker in colorectal cancer PMID: 26254099
    4. Even at early stages of malignant transformation, a significant decrease in ADH1B, ADH3, RDHL, and RALDH1 mRNA levels was observed in 82, 79, 73, and 64% of tumor specimens, respectively PMID: 27239845
    5. Dehydrogenase/reductase SDR family member 9 is a moonlighting protein that functions as both a metabolic enzyme and as a transcriptional repressor. PMID: 16691198
    6. expression of retinol dehydrogenase L is regulated by APC and CDX2 PMID: 15190067
    7. retinoic acid-responsive genes are induced by Epstein-Barr virus lytic infection through induction of a retinol-metabolizing enzyme, DHRS9 PMID: 17244623

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  • 亚细胞定位：
    Microsome membrane. Endoplasmic reticulum membrane. Note=Associated with microsomal membranes.
  • 蛋白家族：
    Short-chain dehydrogenases/reductases (SDR) family
  • 组织特异性：
    Highly expressed in trachea and epidermis. Detected at lower levels in spinal cord, bone marrow, brain, tongue, esophagus, heart, colon, testis, placenta, lung, skeletal muscle and lymph node.
  • 数据库链接：

    HGNC: 16888

    OMIM: 612131

    KEGG: hsa:10170

    STRING: 9606.ENSP00000316670

    UniGene: Hs.179608